Cannabis use and cognitive biases in people with first-episode psychosis and their siblings
Abstract Background: Cannabis use and familial vulnerability to psychosis have been associated with social cognition deficits. This study examined the…
behavior & cognition
FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis
Abstract Background: Chronic Gulf War Illness (GWI) is characterized by cognitive and mood impairments, as well as persistent neuroinflammation and…
Adolescent THC impacts on mPFC dopamine-mediated cognitive processes in male and female rats
Abstract Rationale: Adolescent cannabis use is linked to later-life changes in cognition, learning, and memory. Rodent experimental studies suggest Δ9-tetrahydrocannabinol…
Using Task-fMRI to Explore the Relationship Between Lifetime Cannabis Use and Cognitive Control in Individuals With First-Episode Schizophrenia
Abstract While continued cannabis use and misuse in individuals with schizophrenia is associated with a variety of negative outcomes, individuals…
12-month neurological and psychiatric outcomes of semaglutide use for type 2 diabetes: a propensity-score matched cohort study
Abstract Background: While semaglutide, approved for type-2 diabetes mellitus (T2DM), is being investigated as a treatment for brain disorders, concerns…
Interactions between metabotropic glutamate and CB1 receptors: implications for mood, cognition, and synaptic signaling based on data from mGluR and CB1R-targeting drugs
Abstract Metabotropic glutamate receptors (mGluRs) are part of the G protein-coupled receptors (GPCRs) family. They are coupled to Gαq (group…
Evaluating possible ‘next day’ impairment in insomnia patients administered an oral medicinal cannabis product by night: a pilot randomized controlled trial
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00213-024-06595-9. Article type: Research Article Keywords: cannabinoids, cognition, driving…
Expression Patterns of miRNAs in Egyptian Children with ADHD: Clinical Study with Correlation Analysis
Abstract ADHD has huge knowledge gaps concerning its etiology. MicroRNAs (miRNAs) provide promising diagnostic biomarkers of human pathophysiology and may…
Tetrahydrocannabinol and dopamine D1 receptor
Abstract Dopamine is a hormone that is released by the adrenal gland and influences motor control and motivation. Dopamine is…
Omega-3 Recovers Cannabinoid 1 Receptor Expression in the Adult Mouse Brain after Adolescent Binge Drinking
Abstract Adolescent binge drinking is a social problem with a long-lasting impact on cognitive functions. The cannabinoid type-1 (CB1) receptor…