Integrative transcriptome data mining for identification of core lncRNAs in breast cancer
Abstract Background: Cumulative evidence suggests that long non-coding RNAs (lncRNAs) play an important role in tumorigenesis. This study aims to…
Basal-like breast cancer
Antitumor Activity of Abnormal Cannabidiol and Its Analog O-1602 in Taxol-Resistant Preclinical Models of Breast Cancer
Abstract Cannabinoids exhibit anti-inflammatory and antitumorigenic properties. Contrary to most cannabinoids present in the Cannabis plant, some, such as O-1602…
Heat shock proteins create a signature to predict the clinical outcome in breast cancer
Abstract Utilizing The Cancer Genome Atlas (TCGA) and KM plotter databases we identified six heat shock proteins associated with survival…
Catheter-based delineation of lumpectomy cavity for accurate target definition in partial-breast irradiation with multicatheter interstitial brachytherapy
Abstract Purpose: In partial-breast irradiation (PBI), accurate lumpectomy cavity (LC) delineation is critical. Seroma-based delineation (SBD) using computed tomography (CT)…
Construction of prognostic microRNA signature for human invasive breast cancer by integrated analysis
Abstract Background: Despite the advances in early detection and treatment methods, breast cancer still has a high mortality rate, even…
The expression signature of cancer‐associated KRAB‐ZNF factors identified in TCGA pan‐cancer transcriptomic data
Abstract The KRAB‐ZNF (Krüppel‐associated box domain zinc finger) gene family is composed of a large number of highly homologous genes,…
The onus of cannabinoids in interrupting the molecular odyssey of breast cancer: A critical perspective on UPRER and beyond
Abstract Cannabinoids, commonly used for medicinal and recreational purposes, consist of various complex hydrophobic molecules obtained from Cannabis sativa L.…
GPCRs in Cancer: Protease-Activated Receptors, Endocytic Adaptors and Signaling
Abstract G protein-coupled receptors (GPCRs) are a large diverse family of cell surface signaling receptors implicated in various types of…
The origins of breast cancer associated with mammographic density: a testable biological hypothesis
Abstract Background: Our purpose is to develop a testable biological hypothesis to explain the known increased risk of breast cancer…