Characterization of Clostridium perfringens Phage Endolysin PlyDolk21
Abstract Background: Clostridium perfringens is a significant cause of food poisoning. Broad-spectrum antibiotics, commonly used to control C. perfringens, are…
bacteriophage
New-Generation Antibacterial Agent—Cellulose-Binding Thermostable TP84_Endolysin
Abstract The increasing antibiotic resistance among bacteria challenges the biotech industry to search for new antibacterial molecules. Endolysin TP84_28 is…
Rapid and Specific Detection of Bacillus cereus Using Phage Protein-Based Lateral Flow Assays
Abstract Rapid and precise diagnostic techniques are essential for identifying foodborne pathogens, including Bacillus cereus (B. cereus), which poses significant…
Characteristics of the Enterococcus Phage vB_EfS_SE, and the Properties of Its Chimeric Endolysins Harboring a PlySE-Carbohydrate-Binding Domain and a Synthetic Enzymatic Domain
Abstract Background/Objectives: The World Health Organization has selected enterococci as one of the priority multidrug-resistant microorganisms for the development of…
The New SH3b_T Domain Increases the Structural and Functional Variability Among SH3b-Like CBDs from Staphylococcal Phage Endolysins
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s12602-024-10309-0. Article type: Research Article Keywords: Bacteriophage, Endolysin, Cell…
LysGR1, a novel thermostable endolysin from Geobacillus stearothermophilus bacteriophage GR1
Abstract Geobacillus stearothermophilus is a highly thermophilic, spore-forming Gram-positive bacterium that causes flat sour spoilage in low-acid canned foods. To…
Rapid and High-Throughput Evaluation of Diverse Configurations of Engineered Lysins Using the VersaTile Technique
Abstract Bacteriophage-encoded lysins are an emerging class of antibacterial enzymes based on peptidoglycan degradation. The modular composition of lysins is…
Characterization of PlyB221 and PlyP32, Two Novel Endolysins Encoded by Phages Preying on the Bacillus cereus Group
Abstract Endolysins are phage-encoded enzymes implicated in the breaching of the bacterial cell wall at the end of the viral…
Resistance of Gram-Positive Bacteria to Current Antibacterial Agents and Overcoming Approaches
Abstract The discovery of antibiotics has created a turning point in medical interventions to pathogenic infections, but unfortunately, each discovery…
Ultrasensitive and Fast Diagnostics of Viable Listeria Cells by CBD Magnetic Separation Combined with A511::luxAB Detection
Abstract The genus Listeria includes foodborne pathogens that cause life-threatening infections in those at risk, and sensitive and specific methods…