FMR1 and Autism, an Intriguing Connection Revisited
Abstract Autism Spectrum Disorder (ASD) represents a distinct phenotype of behavioral dysfunction that includes deficiencies in communication and stereotypic behaviors.…
autism models
Cannabidiol and Neurodevelopmental Disorders in Children
Abstract Neurodevelopmental and neuropsychiatric disorders (such as autism spectrum disorder) have broad health implications for children, with no definitive cure…
Cannabis and cannabinoid use in autism spectrum disorder: a systematic review
Abstract Introduction: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by persistent deficits in social communication and social interaction,…
Endocannabinoid System Dysregulation from Acetaminophen Use May Lead to Autism Spectrum Disorder: Could Cannabinoid Treatment Be Efficacious?
Abstract Persistent deficits in social communication and interaction, and restricted, repetitive patterns of behavior, interests or activities, are the core…
Neural Mechanisms Underlying Repetitive Behaviors in Rodent Models of Autism Spectrum Disorders
Abstract Autism spectrum disorder (ASD) is comprised of several conditions characterized by alterations in social interaction, communication, and repetitive behaviors.…
Medicinal Use of Cannabis in Children and Pregnant Women
Abstract The increasing medicinal use of cannabis during recent years has largely overlooked children and pregnant women due to litigious…
Current state of evidence of cannabis utilization for treatment of autism spectrum disorders
Abstract The core symptoms and co-morbidities associated with autism spectrum disorders (ASD) affect daily living and quality of life. Existing…
The Endocannabinoid System as a Window Into Microglial Biology and Its Relationship to Autism
Abstract Microglia are the resident, innate immune cells of the central nervous system (CNS) and are critical in managing CNS…
Cannabis use is associated with potentially heritable widespread changes in autism candidate gene DLGAP2 DNA methylation in sperm
Abstract Parental cannabis use has been associated with adverse neurodevelopmental outcomes in offspring, but how such phenotypes are transmitted is…
Comparative psychopharmacology of autism and psychotic-affective disorders suggests new targets for treatment
Abstract The first treatments showing effectiveness for some psychiatric disorders, such as lithium for bipolar disorder and chlorpromazine for schizophrenia,…