Cannabidiol efficacy independent of clobazam: Meta‐analysis of four randomized controlled trials
Abstract Objective: The efficacy of cannabidiol (CBD) with and without concomitant clobazam (CLB) was evaluated in stratified analyses of four…
audiogenic seizures
Anticonvulsive Properties of Cannabidiol in a Model of Generalized Seizure Are Transient Receptor Potential Vanilloid 1 Dependent
Abstract Introduction: Highly purified cannabidiol (CBD) (approved as Epidiolex® in the United States) has demonstrated efficacy with an acceptable safety…
Anticonvulsant Essential Oils and Their Relationship with Oxidative Stress in Epilepsy
Abstract Epilepsy is a most disabling neurological disorder affecting all age groups. Among the various mechanisms that may result in…
Cannabis Influences the Putative Cytokines-Related Pathway of Epilepsy among Egyptian Epileptic Patients
Abstract The study aims to investigate: (1) the prevalence of cannabis among epileptic patients seen at Mansoura University Hospital, (2)…
Cannabidiol reduces seizures following CNS infection with Theiler’s murine encephalomyelitis virus
Abstract Objective: C57BL/6J mice infected with Theiler’s murine encephalomyelitis virus (TMEV) develop acute behavioral seizures in the first week of…
Single and Synergistic Effects of Cannabidiol and Δ-9-Tetrahydrocannabinol on Zebrafish Models of Neuro-Hyperactivity
Abstract In this study, we aimed to investigate the effect of the two main active cannabinoids extracted from cannabis: Δ-9-tetrahydrocannabinol…
Long‐term cannabidiol treatment in patients with Dravet syndrome: An open‐label extension trial
Abstract Objective: Add‐on cannabidiol (CBD) significantly reduced seizures associated with Dravet syndrome (DS) in a randomized, double‐blind, placebo‐controlled trial: GWPCARE1…
Long‐term safety and treatment effects of cannabidiol in children and adults with treatment‐resistant epilepsies: Expanded access program results
Abstract Objective: Since 2014, cannabidiol (CBD) has been administered to patients with treatment‐resistant epilepsies (TREs) in an ongoing expanded‐access program…
Narrative review of the safety and efficacy of marijuana for the treatment of commonly state-approved medical and psychiatric disorders
Abstract The present investigation aimed to provide an objective narrative review of the existing literature pertaining to the benefits and…
MRI characterisation of adult onset alpha-methylacyl-coA racemase deficiency diagnosed by exome sequencing
Abstract Background: Correct diagnosis is pivotal to understand and treat neurological disease. Herein, we report the diagnostic work-up utilizing exome…