Abstract Cancer is a complex family of diseases affecting millions of people worldwide. Gliomas are primary brain tumors that account…
Abstract Cannabinoids exert anti-cancer actions; however, the underlying cytotoxic mechanisms and the cannabinoid receptors (CBRs) involved remain unclear. In this…
Abstract Cannabinoid receptor 1 (CB1) is a therapeutically relevant drug target for controlling pain, obesity, and other central nervous system…
Abstract Type 1 diabetes mellitus (T1DM) is an autoimmune disease resulting from loss of insulin-secreting β-cells in islets of Langerhans.…
Abstract Background/aim: Nicotine acts as an agonist of nicotinic acetylcholine receptors (nAChR). These receptors belong to a superfamily of ligand-gated…
Abstract The endocannabinoid and orexin neuromodulatory systems serve key roles in many of the same biological functions such as sleep,…
Abstract Cannabinoids (CBs), such as phytocannabinoids, synthetic CBs, and endogenous CBs, can be neuroprotective, rewarding, or aversive. The aversive effects…
Abstract The endocannabinoid (eCB) system has been found in all visual parts of the central ner-vous system and plays a…
Abstract The most important discoveries in pharmacology, such as certain classes of analgesics or chemotherapeutics, started from natural extracts which…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s13311-021-01127-1. Article type: Research Article Keywords: Chemotherapy, Neuropathy, Endocannabinoid…