The relationship between cannabis and anorexia nervosa: a scoping review
Abstract Background: Relapse rates in Anorexia Nervosa (AN) remain high, warranting exploration of further treatments. Cannabinoid agonists are of interest…
atypical cannabinoid receptors
Labour and premature delivery differentially affect the expression of the endocannabinoid system in the human placenta
Abstract Plasma concentrations of N-arachidonyletholamine (AEA), N-oleoylethanolamide (OEA) and N-palmitoylethanolamide (PEA) increase at term and can predict when a woman…
A type II cannabis extract and a 1:1 blend of Δ(9)-tetrahydrocannabinol and cannabidiol display distinct antinociceptive profiles and engage different endocannabinoid targets when administered into the subarachnoid space
Abstract Introduction: Cannabis extracts are being increasingly used to mitigate chronic pain. Current guidelines for their prescription rely on Δ9-tetrahydrocannabinol…
Terminal type-specific cannabinoid CB1 receptor alterations in patients with schizophrenia: A pilot study
Abstract Background: Individuals with schizophrenia are at elevated genetic risks for comorbid cannabis use, and often experience exacerbations of cognitive…
Low Doses of β-Caryophyllene Reduced Clinical and Paraclinical Parameters of an Autoimmune Animal Model of Multiple Sclerosis: Investigating the Role of CB2 Receptors in Inflammation by Lymphocytes and Microglial
Abstract Multiple Sclerosis (MS) is a prevalent inflammatory disease in which the immune system plays an essential role in the…
Motifs in Natural Products as Useful Scaffolds to Obtain Novel Benzo[d]imidazole-Based Cannabinoid Type 2 (CB2) Receptor Agonists
Abstract The endocannabinoid system (ECS) constitutes a broad-spectrum modulator of homeostasis in mammals, providing therapeutic opportunities for several pathologies. Its…
The Expression of the Endocannabinoid Receptors CB2 and GPR55 Is Highly Increased during the Progression of Alzheimer’s Disease in AppNL-G-F Knock-In Mice
Abstract Simple Summary: Alzheimer’s disease (AD) is a complex, multifactorial disease where numerous components, such as environment, lifestyle, comorbidities, and…
The endocannabinoid system and breathing
Abstract Recent changes in cannabis accessibility have provided adjunct therapies for patients across numerous disease states and highlights the urgency…
Terminal type-specific cannabinoid CB1 receptor alterations in patients with schizophrenia: a pilot study
Abstract Background: Individuals with schizophrenia are at elevated genetic risks for comorbid cannabis use, and often experience exacerbations of cognitive…
Cannabidiol as a Modulator of the Development of Alcohol Tolerance in Rats
Abstract The study aimed to explore in vivo the influence of cannabidiol (CBD) on the development of alcohol tolerance in…