Cannabis use during the early COVID-19 pandemic: Use patterns, predictors, and subjective experiences
Abstract Background: Even in the early stages, global crises such as the COVID-19 pandemic lead to serious dislocations of social…
Asymptomatic SARS-CoV-2 infection
Asymptomatic versus symptomatic SARS-CoV-2 infection: a cross-sectional seroprevalence study
Abstract Background: Although symptomatic SARS-CoV-2 infection predisposes patients to develop complications, the asymptomatic SARS-CoV-2 infection state is of public health…
Molecular Modeling Targeting the ACE2 Receptor with Cannabis sativa’s Active Ingredients for Antiviral Drug Discovery against SARS-CoV-2 Infections
Abstract The emergence of a novel coronavirus that later on rendered a global pandemic, caused desperation within the communities and…
Antiviral Potential of Small Molecules Cordycepin, Thymoquinone, and N6, N6-Dimethyladenosine Targeting SARS-CoV-2 Entry Protein ADAM17
Abstract COVID-19 is an acute respiratory disease caused by SARS-CoV-2 that has spawned a worldwide pandemic. ADAM17 is a sheddase…
Systematic analysis of virus nucleic acid sensor DDX58 in malignant tumor
Abstract Introduction: In December 2019, a novel epidemic of coronavirus pneumonia (COVID-19) was reported，and population-based studies had shown that cancer…
Value of Drains in Soft-Tissue Tumour Surgery: A Specialist Regional Centre Experience
Abstract Background The mainstay of therapy in most soft-tissue tumours (STTs) is excision. However, this often results in blood/extracellular fluid…
Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein
Keywords: SARS-CoV-2, Nucleocapsid protein, N-terminal domain, Ceftriaxone sodium Authors: Xiaodong Luan, Xinming Li, Yufan Li, Gengchen Su, Wanchao Yin, Yi…
Antiviral and Anti-Inflammatory Plant-Derived Bioactive Compounds and Their Potential Use in the Treatment of COVID-19-Related Pathologies
Abstract The highly contagious coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been declared a…
Identification of SARS-CoV-2 Main Protease Inhibitors from a Library of Minor Cannabinoids by Biochemical Inhibition Assay and Surface Plasmon Resonance Characterized Binding Affinity
Abstract The replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mediated by its main protease (Mpro), which…
The regulation of ISG20 expression on SARS-CoV-2 infection in cancer patients and healthy individuals
Abstract ISG20 inhibits viruses such as SARS-CoV-2 invasion; however, details of its expression and regulation with viral susceptibility remain to…