Quantifying the Kinetics of Signaling and Arrestin Recruitment by Nervous System G-Protein Coupled Receptors
Abstract Neurons integrate inputs over different time and space scales. Fast excitatory synapses at boutons (ms and μm), and slow…
arrestins
Cannabinoid CB1 and CB2 Receptor-Mediated Arrestin Translocation: Species, Subtype, and Agonist-Dependence
Abstract Arrestin translocation and signaling have come to the fore of the G protein-coupled receptor molecular pharmacology field. Some receptor–arrestin…
GPCRs in Cancer: Protease-Activated Receptors, Endocytic Adaptors and Signaling
Abstract G protein-coupled receptors (GPCRs) are a large diverse family of cell surface signaling receptors implicated in various types of…