Antiseizure Medications: Advancements, Challenges, and Prospects in Drug Development
Abstract Epilepsy is a neurological disorder affecting millions of people worldwide. Antiseizure medications (ASM) remain a critical therapeutic intervention for…
antiseizure medications (ASMs)
Long-term efficacy and adverse effects of cannabidiol in adjuvant treatment of drug-resistant epilepsy: a systematic review and meta-analysis
Abstract Background: Epilepsy is one of the most common chronic brain diseases. Almost one-third of patients have drug-resistant epilepsy (DRE).…
Antiseizure Medications in Alzheimer’s Disease from Preclinical to Clinical Evidence
Abstract Alzheimer’s disease (AD) and epilepsy are common neurological disorders in the elderly. A bi-directional link between these neurological diseases…
Traditional and Innovative Anti-seizure Medications Targeting Key Physiopathological Mechanisms: Focus on Neurodevelopment and Neurodegeneration
Abstract Despite the wide range of compounds currently available to treat epilepsy, there is still no drug that directly tackles…
On-Line Solid Phase Extraction High Performance Liquid Chromatography Method Coupled With Tandem Mass Spectrometry for the Therapeutic Monitoring of Cannabidiol and 7-Hydroxy-cannabidiol in Human Serum and Saliva
Abstract Cannabidiol is a novel antiseizure medication approved in Europe and the US for the treatment of seizures associated with…
DECIDE: a cluster randomized controlled trial to reduce non-medically indicated caesareans in Burkina Faso
Abstract Background: Since 2006, Burkina Faso has subsidized the cost of caesarean sections to increase their accessibility. Caesareans are performed…