Antiproliferative activity

February 5, 2025

Water‐Soluble Curcumin Derivatives Including Aza‐Crown Ether Macrocycles as Enhancers of Their Cytotoxic Activity

Abstract The synthesis of three novel curcumin derivative compounds, featuring aza‐crown ether macrocycles of various sizes (aza‐12‐crown‐4, aza‐15‐crown‐5, and aza‐18‐crown‐6),…

February 10, 2023

In vitro antioxidant, anti-inflammatory, and anticancer activities of mixture Thai medicinal plants

Abstract Background: The phytochemical study of medicinal plants is rapidly gaining popularity with many pharmacologic effects. This study aims to…

June 1, 2021

A conserved motif in human BTG1 and BTG2 proteins mediates interaction with the poly(A) binding protein PABPC1 to stimulate mRNA deadenylation

Abstract Antiproliferative BTG/Tob proteins interact directly with the CAF1 deadenylase subunit of the CCR4-NOT complex. This binding requires the presence…