Novel Insights Into the Bioactive Profile and Therapeutic Potentials of Indonesian Annona muricata Leaves
Abstract This study investigates, for the first time, the comprehensive pharmacological profile of the aqueous extract of Annona muricata L.…
antinociceptive activity
Volatilome and Antinociceptive Activity of the Traditional Preparation and Compounds from Ageratina grandifolia (Regel) R.M. King & H. Rob.
Abstract An infusion of Ageratina grandifolia, a traditional preparation, and major compounds [3,5‐diprenyl‐4‐hydroxyacetophenone (1), O‐methylencecalinol (2), encecalin (3), and encecalinol…
Design, Synthesis, and Evaluation of Antinociceptive Properties of Novel CBD-Based Terpene-Cinnamoyl-Acyl-Hydrazone Analogues
Abstract Background/Objectives: Cannabidiol (CBD) has been reported for its antinociceptive, anti-inflammatory, and neuroprotective activities. However, several legal restrictions on its…
Analysis of Chemical Composition, Antioxidant Capacity, Acute Toxicity, and Antinociceptive Properties of Aqueous Extract of Origanum Majorana L.
Abstract Pharmacological evaluation showed that AEOM significantly reduced pain in an animal model, suggesting potential analgesic properties. Acute toxicity studies…
The Anti-Inflammatory Properties of Terpenoids from Cannabis
Abstract Introduction: Cannabinoids are well known to have anti-inflammatory effects in mammalians; however, the Cannabis plant also contains other compounds…
Antinociceptive Action of Isolated Mitragynine from Mitragyna Speciosa through Activation of Opioid Receptor System
Abstract Cannabinoids and opioids systems share numerous pharmacological properties and antinociception is one of them. Previous findings have shown that…