Antidepressant-like effects of cannabidiol when combined with temozolomide in adult rats
Abstract There is a need for characterizing more efficacious therapeutic strategies for glioblastoma multiforme to overcome treatment resistance to the…
antidepressants
Skin on Drugs: Psychotropic Compounds in Cutaneous Biology
Abstract Recent evidence reveals that several psychotropic compounds exert significant biological effects on the skin through neurochemical and immunomodulatory pathways.…
Depression and Anxiety as Comorbidities in Chronic Obstructive Pulmonary Disease: A Comprehensive Narrative Review
Abstract Background: Chronic Obstructive Pulmonary Disease (COPD) is a prevalent, progressive condition often associated with psychiatric comorbidities such as depression…
Pharmacological mechanism of natural antidepressants: the role of epigenetic modifications
Abstract MDD is a complex mental illness shaped by the interplay between genetic vulnerability and environmental triggers. Its underlying pathophysiological…
Trends in Antidepressant, Anxiolytic, and Cannabinoid Use Among Italian Elite Athletes (2011–2023): A Longitudinal Anti-Doping Analysis
Abstract Mental health disorders, particularly depression and anxiety, have become increasingly prevalent among elite athletes, exacerbated by factors such as…
Patterns in (es)citalopram prescriptions to Medicaid and Medicare patients in the United States: the potential effects of evergreening
Abstract Introduction: Citalopram and escitalopram are among the most used medications and are key treatments for many psychiatric disorders. Previous…
Involvement of CB1R and CB2R Ligands in Sleep Disorders and Addictive Behaviors in the Last 25 Years
Abstract Over the last three decades, the decriminalization and legalization of therapeutic and recreational marijuana consumption have increased. Consequently, the…
Applying Natural Language Processing Techniques to Map Trends in Insomnia Treatment Terms on the r/Insomnia Subreddit: Infodemiology Study
Abstract Background: People share health-related experiences and treatments, such as for insomnia, in digital communities. Natural language processing tools can…
Green rush and red warnings: Retrospective chart review of adverse events of interactions between cannabinoids and psychotropic drugs
Abstract Aim: Our objective was to systematically assess the prevalence and clinical features of adverse events related to interactions between…
Pharmacological Treatment of Fibromyalgia Syndrome: A Practice-Based Review
Abstract Purpose of Review: Fibromyalgia Syndrome (FMS) is a complex chronic pain condition characterized by widespread musculoskeletal pain and numerous…