A pan-cancer survey of cell line tumor similarity by feature-weighted molecular profiles
Abstract Patient-derived cell lines are often used in pre-clinical cancer research, but some cell lines are too different from tumors…
anticancer therapy
Molecular Mechanism of Autophagy and Its Regulation by Cannabinoids in Cancer
Abstract Simple Summary: This review examines the complex function of autophagy in malignancy and explores its regulation by cannabinoids in…
Multiomics Analysis Reveals that GLS and GLS2 Differentially Modulate the Clinical Outcomes of Cancer
Abstract Kidney-type glutaminase (GLS) and liver-type glutaminase (GLS2) are dysregulated in many cancers, making them appealing targets for cancer therapy.…
Protein calorie malnutrition, nutritional intervention and personalized cancer care
Abstract Cancer patients often experience weight loss caused by protein calorie malnutrition (PCM) during the course of the disease or…