Synthesis, Molecular Docking, and Biological Studies of New Naphthalene‐1,4‐Dione‐Linked Phenylpiperazine and Thioether
Abstract Quinones are an important family of chemical compounds that are used in the development of anticancer drugs. Due to…
anticancer activity
Complex forming properties of cannabinoid acids in a green solvent and bioassays focused on gastric disease caused by Helicobacter pylori infection
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-03442-5. Article type: Research Article Keywords: Cannabinoid acids, Copper(II)…
Extraction of Cannabinoids and Terpenes from Hemp Flowers and Leaves (Cannabis sativa L., Futura 75): Chemical Profiling and Evaluation of Anticancer Properties
Abstract This study investigated efficient extraction methods for cannabinoids and terpenes from the above-ground parts of Futura 75, focusing on…
The Anticancer Activity of Cannabinol (CBN) and Cannabigerol (CBG) on Acute Myeloid Leukemia Cells
Abstract Several cannabis plant-derived compounds, especially cannabinoids, exhibit therapeutic potential in numerous diseases and conditions. In particular, THC and CBD…
The anticancer activity of bile acids in drug discovery and development
Abstract Bile acids (BAs) constitute essential components of cholesterol metabolites that are synthesized in the liver, stored in the gallbladder,…
Genome-Scale Metabolic Reconstruction, Non-Targeted LC-QTOF-MS Based Metabolomics Data, and Evaluation of Anticancer Activity of Cannabis sativa Leaf Extracts
Abstract Over the past decades, Colombia has suffered complex social problems related to illicit crops, including forced displacement, violence, and…
Cannabidiol on the Path from the Lab to the Cancer Patient: Opportunities and Challenges
Abstract Cannabidiol (CBD), a major non-psychotropic component of cannabis, is receiving growing attention as a potential anticancer agent. CBD suppresses…
Chemical characterization of non‐psychoactive Cannabis sativa L. extracts, in vitro antiproliferative activity and induction of apoptosis in chronic myelogenous leukaemia cancer cells
Abstract In this study, extracts from non‐psychoactive Cannabis sativa L. varieties were characterized by means of ultra high‐performance liquid chromatography…
mTOR/EGFR/iNOS/MAP2K1/FGFR/TGFB1 Are Druggable Candidates for N-(2,4-Difluorophenyl)-2′,4′-Difluoro-4-Hydroxybiphenyl-3-Carboxamide (NSC765598), With Consequent Anticancer Implications
Abstract Background: The application of computational and multi-omics approaches has aided our understanding of carcinogenesis and the development of therapeutic…