Critical review on the efficacy and safety of levobupivacaine peritonsillar infiltration
Abstract Levobupivacaine is a long-acting local anesthetic that is both safe and non-toxic. However, few researchers have examined the efficacy…
anti-tumor efficacy
Clinical Trials of Cannabidiol for Substance Use Disorders: Outcome Measures, Surrogate Endpoints, and Biomarkers
Abstract Background: Cannabidiol (CBD) is a cannabinoid of potential interest for the treatment of substance use disorders. Our aim was…
Cannabidiol in the Treatment of Epilepsy: A Focused Review of Evidence and Gaps
Abstract Approximately one third of epilepsy patients do not become seizure free with antiseizure medications. This treatment gap motivates research…
Lack of evidence for the effectiveness or safety of over-the-counter cannabidiol products
Abstract Over the past 5 years, public interest in the potential health benefits of cannabidiol (CBD) has increased exponentially, and…
Add‐on cannabidiol significantly decreases seizures in 3 patients with SYNGAP1 developmental and epileptic encephalopathy
Abstract Mutations in SYNGAP1 are associated with developmental delay, epilepsy, and autism spectrum disorder (ASD). Epilepsy is often drug‐resistant in…
Dosage, Efficacy and Safety of Cannabidiol Administration in Adults: A Systematic Review of Human Trials
Abstract Considering data from in vitro and in vivo studies, cannabidiol (CBD) seems to be a promising candidate for the…
Use of Herbal Medicine by Pregnant Women: What Physicians Need to Know
Abstract About 80% of the consumers worldwide use herbal medicine (HMs) or other natural products. The percentage may vary significantly…
Pan-Cancer analysis of the expression and regulation of matrisome genes across 32 tumor types
Abstract The microenvironment plays a central role in cancer, and neoplastic cells actively shape it to their needs by complex…
Cannabinoids and Pain: New Insights From Old Molecules
Abstract Cannabis has been used for medicinal purposes for thousands of years. The prohibition of cannabis in the middle of…
Cannabis for pediatric epilepsy: protocol for a living systematic review
Abstract Background: Pediatric epilepsy, including treatment-resistant forms, has a major effect on the quality of life, morbidity, and mortality of…