Abstract There is considerable interest in cannabinoid-based therapies to treat pain, but activation of the endogenous cannabinoid (endocannabinoid) system can…
Abstract Background: Voltage-gated sodium channels regulate dorsal root ganglion excitability and are critical for nociceptive transmission. Cannabidiol (CBD) and related…
Abstract Background: Chronic pain, which is often unrelated to ongoing injury, is poorly understood and difficult to treat. Genetic studies…
Abstract Cannabis sativa root has traditionally been used to relieve pain and inflammation, but its pharmacological properties remain underexplored due…