Functional Role of Transient Receptor Potential Channels in Immune Cells and Epithelia
Abstract Transient receptor potential (TRP) ion channels are widely expressed in several tissues throughout the mammalian organism. Originally, TRP channel…
Anti-inflammatory cytokines
Evaluation of Oxidant/Antioxidant Status and Cytokine Levels in Patients with Cannabis Use Disorder
Abstract Objective: Cannabis is the most commonly used illegal drug in the world and it has several adverse effects such…
Effects of JWH015 in cytokine secretion in primary human keratinocytes and fibroblasts and its suitability for topical/transdermal delivery
Abstract Background: JWH015 is a cannabinoid (CB) receptor type 2 agonist that produces immunomodulatory effects. Since skin cells play a…
Synthetic Cannabinoid-Induced Immunosuppression Augments Cerebellar Dysfunction in Tetanus-Toxin Treated Mice
Abstract Synthetic cannabinoids are one of most abused new psychoactive substances. The recreational use of abused drug has aroused serious…
Crosstalk between endocannabinoid and immune systems: a potential dysregulation in depression?
Abstract Background: The endocannabinoid (eCB) system, an endogenous lipid signaling system, appears to be dysregulated in depression. The role of…
Δ9-THC and N-arachidonoyl glycine regulate BV-2 microglial morphology and cytokine release plasticity: implications for signaling at GPR18
Abstract Microglial cells are extremely plastic and undergo a variety of CNS-prompted shape changes relative to their location and current…
Cancer cachexia—pathophysiology and management
Abstract About half of all cancer patients show a syndrome of cachexia, characterized by anorexia and loss of adipose tissue…
Cachexia and aging: An update based on the fourth international cachexia meeting
Abstract This manuscript highlights the new developments in the pathophysiology of anorexia, cachexia and sarcopenia, based on presentations given at…