The Role of NSUN Family Genes in m5C Methylation and Diseases
Abstract 5-Methylcytosine (m5C) methylation is a widely present nucleic acid modification in various RNAs and is a reversible epigenetic modification…
anti-inflammatory agents
Herbal remedies for oral and dental health: a comprehensive review of their multifaceted mechanisms including antimicrobial, anti-inflammatory, and antioxidant pathways
Abstract Across diverse cultures, herbal remedies have been used to alleviate oral discomfort and maintain dental hygiene. This review presents…
Anti-inflammatory effect of curcuminoids and their analogs in hyperosmotic human corneal limbus epithelial cells
Abstract Background: To assess the efficacy of curcuminoids (curcumin, demethoxycurcumin, bisdemethoxycurcumin [BDC]) and their analogs (tetrahydrocurcumin [THC], tetrahydrodemethoxycurcumin [THDC], tetrahydrobisdemethoxycurcumin)…
Therapeutic Potential and Predictive Pharmaceutical Modeling of Stilbenes in Cannabis sativa
Abstract Cannabis sativa is a plant used for recreational and therapeutic purposes; however, many of the secondary metabolites in the…
The CB2 Receptor as a Novel Therapeutic Target for Epilepsy Treatment
Abstract Epilepsy is characterized by repeated spontaneous bursts of neuronal hyperactivity and high synchronization in the central nervous system. It…
The Therapeutic Potential of Cannabis in Counteracting Oxidative Stress and Inflammation
Abstract Significant growth of interest in cannabis (Cannabis sativa L.), especially its natural anti-inflammatory and antioxidative properties, has been observed…
Epigenetic Regulation of Cannabinoid-Mediated Attenuation of Inflammation and Its Impact on the Use of Cannabinoids to Treat Autoimmune Diseases
Abstract Chronic inflammation is considered to be a silent killer because it is the underlying cause of a wide range…
Cannabinoids: A New Perspective on Epileptogenesis and Seizure Treatment in Early Life in Basic and Clinical Studies
Abstract Neural hyperexcitability in the event of damage during early life, such as hyperthermia, hypoxia, traumatic brain injury, status epilepticus,…
Glucocorticoid-Induced Leucine Zipper: A Promising Marker for Monitoring and Treating Sepsis
Abstract Sepsis is a clinical syndrome that resulting from a dysregulated inflammatory response to infection that leads to organ dysfunction.…
Pyrazolyl-Ureas as Interesting Scaffold in Medicinal Chemistry
Abstract The pyrazole nucleus has long been known as a privileged scaffold in the synthesis of biologically active compounds. Within…