Peroxisomes, PPARs, and Their Role in Macrophages
Abstract Macrophages are versatile immune cells capable of modifying their functions based on their location and the specific requirements of…
anti-inflammation activity
Cannabis sativa Root Extract Exerts Anti-Nociceptive and Anti-Inflammatory Effects via Endocannabinoid Pathway Modulation In Vivo and In Vitro
Abstract Cannabis sativa root has traditionally been used to relieve pain and inflammation, but its pharmacological properties remain underexplored due…
Exosomes-Based Nanotherapeutic Strategies: An Important Approach for Spinal Cord Injury Repair
Abstract The repair and functional regeneration of spinal cord injury (SCI) remains a major challenge and focal point in regenerative…
Promising Dietary Supplements with Potential Senotherapeutic Effects: Aqueous Extracts from Enzymatically Hydrolysed Hemp Seed Cake Flour and Hemp Seed Protein Concentrate
Abstract In the present study, the primary by-products of the hemp-seed oil process—hemp seed cake flour and hemp seed protein…
Complement dysregulation in human tauopathies
Abstract Dysregulation of the complement system plays an important role in the pathogenesis of neurodegenerative diseases, including Alzheimer’s disease (AD).…
Structure modification of luteolin and the influence of its derivatives on biological activities
Abstract Introduction: This research aims to synthesize luteolin derivatives from hemp seeds by means of chemical synthesis, improve the synthesis…
The Therapeutic Potential of Cannabidiol in the Management of Temporomandibular Disorders and Orofacial Pain
Abstract Background: Temporomandibular disorders (TMDs) are a group of conditions affecting the temporomandibular joint (TMJ) and associated muscles, leading to…
A novel insight into the antidepressant effect of cannabidiol: possible involvement of the 5-HT1A, CB1, GPR55, and PPARγ receptors
Abstract Background: Depression is a prevalent and disabling disorder that poses serious problems in mental health care, and rapid antidepressants…
Cannabidiol (CBD) Protects Lung Endothelial Cells from Irradiation-Induced Oxidative Stress and Inflammation In Vitro and In Vivo
Abstract Radiotherapy remains a central pillar in the therapy of solid tumors, including lung cancer. However, the clinically applied radiation…
Antibacterial phenolic compounds from the flowering plants of Asia and the Pacific: coming to the light
Abstract Context: The emergence of pan-resistant bacteria requires the development of new antibiotics and antibiotic potentiators. Objective: This review identifies…