The impact of cannabis use on ageing and longevity: a systematic review of research insights
Abstract Background: With aging emerging as a global challenge linked to chronic diseases, identifying interventions that support a healthy lifespan…
Anti-ageing
An improved epigenetic counter to track mitotic age in normal and precancerous tissues
Abstract The cumulative number of stem cell divisions in a tissue, known as mitotic age, is thought to be a…
Hippocampal Deletion of CB1 Receptor Impairs Social Memory and Leads to Age-Related Changes in the Hippocampus of Adult Mice
Abstract Endocannabinoid system activity declines with age in the hippocampus, along with the density of the cannabinoid receptor type-1 (CB1).…
Epigenomic and Other Evidence for Cannabis-Induced Aging Contextualized in a Synthetic Epidemiologic Overview of Cannabinoid-Related Teratogenesis and Cannabinoid-Related Carcinogenesis
Abstract Background: Twelve separate streams of empirical data make a strong case for cannabis-induced accelerated aging including hormonal, mitochondriopathic, cardiovascular,…
Age-dependent hormesis-like effects of the synthetic cannabinoid CP55940 in C57BL/6 mice
Abstract Use of cannabis and cannabinoid-containing substances is increasing among geriatric patients, despite relatively sparse preclinical evidence in aged models.…
From sunscreens to medicines: Can a dissipation hypothesis explain the beneficial aspects of many plant compounds?
Abstract Medicine has utilised plant‐based treatments for millennia, but precisely how they work is unclear. One approach is to use…