Chemical Constituents and Biological Activities of Oxandra (Annonaceae): A Review
Abstract Oxandra (Annonaceae) comprises 29 species distributed across South and Central America. Despite this diversity, the genus remains under‐investigated. This…
anonnaceae
Low Doses of β-Caryophyllene Reduced Clinical and Paraclinical Parameters of an Autoimmune Animal Model of Multiple Sclerosis: Investigating the Role of CB2 Receptors in Inflammation by Lymphocytes and Microglial
Abstract Multiple Sclerosis (MS) is a prevalent inflammatory disease in which the immune system plays an essential role in the…
Therapeutic Potential of Phytocannabinoid Cannabigerol for Multiple Sclerosis: Modulation of Microglial Activation In Vitro and In Vivo
Abstract Multiple sclerosis (MS) is a widespread chronic neuroinflammatory and neurodegenerative disease. Microglia play a crucial role in the pathogenesis…
Crosstalk between the M1 muscarinic acetylcholine receptor and the endocannabinoid system: A relevance for Alzheimer’s disease?
Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder which accounts for 60–70% of the 50 million worldwide cases of dementia…
Combination of Cannabinoids, Δ9- Tetrahydrocannabinol and Cannabidiol, Ameliorates Experimental Multiple Sclerosis by Suppressing Neuroinflammation Through Regulation of miRNA-Mediated Signaling Pathways
Abstract Multiple sclerosis (MS) is a chronic and disabling disorder of the central nervous system (CNS) characterized by neuroinflammation leading…
CB1 Agonism Alters Addiction-Related Behaviors in Mice Lacking Mu or Delta Opioid Receptors
Abstract Opioids are powerful analgesics but the clinical utility of these compounds is reduced by aversive outcomes, including the development…
Anti-invasion Effects of Cannabinoids Agonist and Antagonist on Human Breast Cancer Stem Cells
Abstract Studies show that cancer cell invasion or metastasis is the primary cause of death in malignancies including breast cancer.…