The zinc-finger protein Red1 orchestrates MTREC submodules and binds the Mtl1 helicase arch domain
Abstract Cryptic unstable transcripts (CUTs) are rapidly degraded by the nuclear exosome in a process requiring the RNA helicase Mtr4…
animal and plant proteins
The Effect of Protein Source on the Physicochemical, Nutritional Properties and Microstructure of High-Protein Bars Intended for Physically Active People
Abstract The purpose of this study was to investigate the effect of protein sources (algae, pumpkin, wheat, sunflower, rice, soy,…
Yeast Spt6 Reads Multiple Phosphorylation Patterns of RNA Polymerase II C-Terminal Domain In Vitro
Abstract Transcription elongation factor Spt6 associates with RNA polymerase II (RNAP II) via a tandem SH2 (tSH2) domain. The mechanism…
Dose-dependent effect of cannabinoid WIN-55,212-2 on myelin repair following a demyelinating insult
Abstract Dysfunctions in the endocannabinoid system have been associated with experimental animal models and multiple sclerosis patients. Interestingly, the endocannabinoid…
A genome-wide screen for human salicylic acid (SA)-binding proteins reveals targets through which SA may influence development of various diseases
Abstract Salicylic acid (SA) is the major metabolite and active ingredient of aspirin; both compounds reduce pain, fever, and inflammation.…
Effect of Pharmacological Modulation of the Endocannabinoid System on Opiate Withdrawal: A Review of the Preclinical Animal Literature
Abstract Over the years, animal studies have revealed a role for the endocannabinoid system in the regulation of multiple aspects…
Studying the Structure and Dynamics of Biomolecules by Using Soluble Paramagnetic Probes
Abstract Characterisation of the structure and dynamics of large biomolecules and biomolecular complexes by NMR spectroscopy is hampered by increasing…