An elevated rate of whole-genome duplications in cancers from Black patients
Abstract In the United States, Black individuals have higher rates of cancer mortality than any other racial group. Here, we…
Aneuploidy
The unfolded protein response links tumor aneuploidy to local immune dysregulation
Abstract Aneuploidy is a chromosomal abnormality associated with poor prognosis in many cancer types. Here, we tested the hypothesis that…
Loss of Integrase Interactor 1 (INI1) Expression in a Subset of Differentiated Thyroid Cancer
Abstract Alterations in the switching defective/sucrose non-fermenting (SWI/SNF) chromatin-remodeling complex are enriched in advanced thyroid cancer. Integrase interactor 1 (INI1),…