Potential tumor-specific antigens and immune landscapes identification for mRNA vaccine in thyroid cancer
Abstract Background: Tumor mRNA vaccines have been identified as a promising technology for cancer therapy in multiple cancer types, while…
Anaplastic thyroid cancer (ATC)
Pan-cancer analysis of the immunological and oncogenic roles of ATAD2 with verification in papillary thyroid carcinoma
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-73274-2. Article type: Research Article Keywords: ATAD2, Pan-cancer, Papillary…
Causal effect of thyroid cancer on secondary primary malignancies: findings from the UK Biobank and FinnGen cohorts
Abstract Background: Existing epidemiological data indicated a correlation between thyroid cancer (THCA) and the risk of secondary primary malignancies (SPMs).…
Construction of thyroid cancer classification and iodine metabolism related diagnostic model using thyroid differentiation score and bioinformation
Abstract To more accurately diagnose and treat patients with different subtypes of thyroid cancer, we constructed a diagnostic model related…
SPRED3 regulates the NF-κB signaling pathway in thyroid cancer and promotes the proliferation
Abstract SPRED3 (Sprouty-related EVH1 domain containing 3) mutants are depicted in various cancers, however, nothing is known about its biofunction…
FN1, a reliable prognostic biomarker for thyroid cancer, is associated with tumor immunity and an unfavorable prognosis
Abstract Thyroid cancer (THCA) is a malignant tumor that affects the endocrine system. At present, an effective treatment for THCA…
CTHRC1 is associated with BRAF(V600E) mutation and correlates with prognosis, immune cell infiltration, and drug resistance in colon cancer, thyroid cancer, and melanoma
Abstract Colon cancer, thyroid cancer, and melanoma are common malignant tumors that seriously threaten human health globally. The B-Raf proto-oncogene,…
Identification of signature genes and immune infiltration analysis in thyroid cancer based on PANoptosis related genes
Abstract Background: Thyroid cancer is the most common malignancy of the endocrine system. PANoptosis is a specific form of inflammatory…
Revolutionary multi-omics analysis revealing prognostic signature of thyroid cancer and subsequent in vitro validation of SNAI1 in mediating thyroid cancer progression through EMT
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s10238-024-01387-z. Article type: Research Article Keywords: Multi-omics analysis, Thyroid…
Epigenetic Regulation of DLK1-DIO3 Region in Thyroid Carcinoma
Abstract Non-coding RNAs (ncRNAs) have emerged as pivotal regulators in cellular biology, dispelling their former perception as ‘junk transcripts’. Notably,…