TRIM21‑a potential biomarker for the prognosis of thyroid cancer
Abstract Thyroid cancer (THCA) is one of the commonest malignancies associated with increased recurrence. Therefore, identifying the putative molecular markers…
Anaplastic thyroid cancer (ATC)
Construction of a ferroptosis-related eight gene signature for predicting the prognosis and immune infiltration of thyroid cancer
Abstract Background: Thyroid cancer is the most common malignant tumor of the endocrine system. Most patients with thyroid cancer have…
Effect of the m6ARNA gene on the prognosis of thyroid cancer, immune infiltration, and promising immunotherapy
Abstract Background: Accumulating evidence suggests that N6-methyladenosine (m6A) RNA methylation plays an important role in tumor proliferation and growth. However,…
Disulfiram/Copper Suppresses Cancer Stem Cell Activity in Differentiated Thyroid Cancer Cells by Inhibiting BMI1 Expression
Abstract Differentiated thyroid carcinomas (DTCs), which have papillary and follicular types, are common endocrine malignancies worldwide. Cancer stem cells (CSCs)…
CAPN8 involves with exhausted, inflamed, and desert immune microenvironment to influence the metastasis of thyroid cancer
Abstract Background: Thyroid cancer (THCA) is the most prevalent malignant disease of the endocrine system, in which 5-year survival can…
Integrated analysis of fibroblasts molecular features in papillary thyroid cancer combining single-cell and bulk RNA sequencing technology
Abstract Background: Papillary thyroid cancer (PTC) is the most common pathological type of thyroid cancer with a high incidence globally.…
Construction and validation of a novel prognostic model for thyroid cancer based on N7-methylguanosine modification-related lncRNAs
Abstract Methods: In this study, we identified m7G-lncRNAs using co-expression analysis and performed differential expression analysis of m7G-lncRNAs between groups.…
MEG3 Expression Indicates Lymph Node Metastasis and Presence of Cancer-Associated Fibroblasts in Papillary Thyroid Cancer
Abstract Papillary thyroid cancer is the most common endocrine malignancy, occurring at an incidence rate of 12.9 per 100,000 in…
Effect of FOXP2 transcription factor on immune infiltration of thyroid cancer and its potential clinical value
Abstract Background: The clinical outcomes are not always favorable in certain thyroid cancer patients. The effect of Forkhead-box family on…
Adrenomedullin2 stimulates progression of thyroid cancer in mice and humans under nutrient excess conditions
Abstract Thyroid cancer is associated with genetic alterations, e.g. BRAFV600E, which may cause carcinomatous changes in hormone‐secreting epithelial cells. Epidemiological…