Abstract Chronic pain patients report analgesic effects when using cannabidiol (CBD), a phytocannabinoid found in whole-plant cannabis extract (WPE). Several…
Abstract Background: The endocannabinoid 2-Arachidonyl glycerol (2-AG) exerts dose-related anti-nociceptive effects, which are potentiated by the related but inactive 2-palmitoyl…
Abstract The objective of this paper was to investigate the published evidence regarding effects of cannabinoids (natural and synthetic) on…
Abstract Toll-like receptor 4 (TLR4) is a pattern-recognition receptor (PRR) that regulates the activation of immune cells, which is a…
Abstract A 14-year-old intact mixed breed dog (26 kg) was submitted for a novel cannabidiol (CBD) analgesic treatment. The dog…
Abstract The extensive involvement of the endocannabinoid system (ECS) in vital physiological and cognitive processes of the human body has…
Abstract Background: Recent work has shed light on the potential benefits of cannabinoids for multimodal pain control following orthopedic procedures.…
Abstract Chronic pain is a common detrimental condition that affects around 20% of the world population. The current drugs to…
Abstract Cannabis has been used in pain management since 2900 BC. In the 20th century, synthetic cannabinoids began to emerge,…
Abstract A randomized, placebo-controlled crossover trial utilizing vaporized cannabis containing placebo and 6.7% and 2.9% delta-9-tetrahydrocannabinol (THC) was performed in…