Solution Structure of the Broad-Spectrum Bacteriocin Garvicin Q
Abstract Class IId bacteriocins are linear, unmodified antimicrobial peptides produced by Gram-positive bacteria, and often display potent, narrow-spectrum inhibition spectra.…
Alternatives to antibiotics
Chemical Composition and Synergistic Antimicrobial Effects of Essential Oils From Four Commonly Used Satureja Species in Combination With Two Conventional Antibiotics
Abstract The chemical composition and the antimicrobial potency of four Satureja essential oils (EOs), and their synergism with two antimicrobials…
Identification of cell wall binding domains and repeats in Streptococcus pneumoniae phage endolysins: A molecular and diversity analysis
Abstract Streptococcus pneumoniae (pneumococcus) is a multidrug-resistant pathogen associated with pneumonia, otitis media, meningitis and other severe complications that are…
Efficacy and Safety of Gepotidacin as Treatment of Uncomplicated Urogenital Gonorrhea (EAGLE-1): Design of a Randomized, Comparator-Controlled, Phase 3 Study
Abstract Introduction: Gonorrhea, caused by Neisseria gonorrhoeae (NG), is the second most common bacterial sexually transmitted infection (STI). Rates of…
Altered endocannabinoidome bioactive lipid levels accompany reduced DNBS-induced colonic inflammation in germ-free mice
Abstract Background: Gut microbiota are involved in the onset and development of chronic intestinal inflammation. The recently described endocannabinoidome (eCBome),…
Antibacterial, Antibiofilm, and Antioxidant Activity of 15 Different Plant-Based Natural Compounds in Comparison with Ciprofloxacin and Gentamicin
Abstract Plant-based natural compounds (PBCs) are comparatively explored in this study to identify the most effective and safe antibacterial agent/s…
Potential cannabidiol (CBD) repurposing as antibacterial and promising therapy of CBD plus polymyxin B (PB) against PB-resistant gram-negative bacilli
Abstract This study aimed to assess the ultrapure cannabidiol (CBD) antibacterial activity and to investigate the antibacterial activity of the…
The antimicrobial potential of cannabidiol
Abstract Antimicrobial resistance threatens the viability of modern medicine, which is largely dependent on the successful prevention and treatment of…
Innovative Animal Model of DSS-Induced Ulcerative Colitis in Pseudo Germ-Free Mice
Abstract The aim of this study was to investigate the use of a standardized animal model subjected to antibiotic treatment,…
Rapid Antibacterial Activity of Cannabichromenic Acid against Methicillin-Resistant Staphylococcus aureus
Abstract Methicillin-resistant Staphylococcus aureus (MRSA) has proven to be an imminent threat to public health, intensifying the need for novel…