Abstract Background: The incidence of thyroid cancer (THCA) continues to increase in recent decades. Accumulating evidence showed that the unbalanced…
Abstract Most opioid analgesics used clinically, including morphine and fentanyl, as well as the recreational drug heroin, act primarily through…
Abstract As a key mechanism, alternative splicing (AS) plays a role in the cancer initiation and development. However, in papillary…
Abstract Alternative splicing (AS) is a key mechanism involved in regulating gene expression and is closely related to tumorigenesis. The…
Abstract As the most critical alternative splicing regulator, heterogeneous nuclear ribonucleoproteins (hnRNPs) have been reported to be implicated in various…
Abstract In this review, Rambout and Maquat discuss known roles of the nuclear cap-binding complex (CBC) during the transcription of…
Abstract Recent findings indicate that allele-specific expression (ASE) at specific cancer driver gene loci may be of importance in onset/progression…
Abstract Background: Dysregulation of alternative splicing (AS) is a critical signature of cancer. However, the regulatory mechanisms of cancer-specific AS…
Abstract Splicing perturbation in cancers contribute to different aspects of cancer cell progression. However, the complete functional impact of cancer-associated…
Abstract Papillary thyroid carcinoma (PTC) is the fastest-growing disease caused by numerous molecular alterations in addition to previously reported DNA…