Internalizing Pathways to Adolescent Substance Use from Adverse Childhood Experiences
Abstract The mediating role of anxious, depressive, and somatic symptoms was examined in the association between adverse childhood experiences (ACEs)…
affective and anxiety
Social Media Exposure and Other Correlates of Increased e-Cigarette Use Among Adolescents During Remote Schooling: Cross-Sectional Study
Abstract Background: Little is known about the role of exposure to e-cigarette–related digital content, behavioral and mental health factors, and…
The Interplay of Exogenous Cannabinoid Use on Anandamide and 2-Arachidonoylglycerol in Anxiety: Results from a Quasi-Experimental Ad Libitum Study
Abstract The public is increasingly reporting using cannabis for anxiety relief. Both cannabis use and the endocannabinoid system have been…
Cannabidiol, a plant-derived compound, is an emerging strategy for treating cognitive impairments: comprehensive review of randomized trials
Abstract Background: Finding new strategies to treat cognitive disorders is a challenging task. Medication must defeat the blood–brain barrier. Cannabidiol…
The Impacts of Adolescent Cannabinoid Exposure on Striatal Anxiety- and Depressive-Like Pathophysiology Are Prevented by the Antioxidant N-Acetylcysteine
Abstract Background: Exposure to Δ9-tetrahydrocannabinol (THC) is an established risk factor for later-life neuropsychiatric vulnerability, including mood- and anxiety-related symptoms.…
Acute effects of cannabigerol on anxiety, stress, and mood: a double-blind, placebo-controlled, crossover, field trial
Abstract Cannabigerol (CBG) is a phytocannabinoid increasing in popularity, with preclinical research indicating it has anxiolytic and antidepressant effects. However,…
Effects of cannabidiol, with and without ∆9-tetrahydrocannabinol, on anxiety-like behavior following alcohol withdrawal in mice
Abstract Introduction: Alcohol use disorder (AUD) is commonly associated with anxiety disorders and enhanced stress-sensitivity; symptoms that can worsen during…
An observational time-series study on the behavioral effects of adjunctive artisanal cannabidiol use by adults with treatment resistant epilepsies
Abstract Background: For approximately 30% of people with epilepsy, seizures are not well-controlled by anti-seizure medication (ASM). This condition, called…
Marijuana use among community-dwelling older adults: A population-based study
Abstract Objectives: There is a paucity of population-level data on marijuana use and mental health and functioning in older adults.…
Substance Use and Anxiety About Pain Among Patients Seeking Abortion Services
Abstract Objectives: To evaluate how recent opioid, marijuana, and cannabidiol use affects pre-procedure pain-related anxiety for patients seeking abortion. Methods:…