The Endocannabinoid System and Invertebrate Neurodevelopment and Regeneration
Abstract Cannabis has long been used for its medicinal and psychoactive properties. With the relatively new adoption of formal medicinal…
AEA
Targeting the endocannabinoid system for management of HIV-associated neuropathic pain: A systematic review
Abstract Human immunodeficiency virus (HIV) infection and antiretroviral therapy can independently induce HIV-associated neuropathic pain (HIV-NP). There is a dearth…
Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders
Abstract Though there is limited research confirming the purported topical benefits of cannabinoids, it is certain that cutaneous biology is…
Cannabinoids, Endocannabinoids and Sleep
Abstract Sleep is a vital function of the nervous system that contributes to brain and bodily homeostasis, energy levels, cognitive…
Crosstalk between the M1 muscarinic acetylcholine receptor and the endocannabinoid system: A relevance for Alzheimer’s disease?
Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder which accounts for 60–70% of the 50 million worldwide cases of dementia…
Peripheral endocannabinoid concentrations are not associated with verbal memory impairment during MDMA intoxication
Abstract Background: Preclinical data have suggested involvement of the endocannabinoid (eCB) system in MDMA-induced memory impairment. Clinical research has shown…
A Personal Retrospective: Elevating Anandamide (AEA) by Targeting Fatty Acid Amide Hydrolase (FAAH) and the Fatty Acid Binding Proteins (FABPs)
Abstract This perspective was adapted from a Career Achievement Award talk given at the International Cannabinoid Research Society Symposium in…
Effects of anandamide in migraine: data from an animal model
Abstract Systemic nitroglycerin (NTG) produces spontaneous-like migraine attacks in migraine sufferers and induces a condition of hyperalgesia in the rat…
Identification of Yju3p as functional orthologue of mammalian monoglyceride lipase in the yeast Saccharomycescerevisiae
Abstract Monoacylglycerols (MAGs) are short-lived intermediates of glycerolipid metabolism. Specific molecular species, such as 2-arachidonoylglycerol, which is a potent activator…