Clinical and functional significance of SPATA2 in cancer particularly in LIHC
Abstract Spermatogenesis-associated protein 2 (SPATA2) is primarily named for its important role in spermatogenesis. Its function in tumorigenesis remains elusive.…
Advanced cancer
Oncological and Survival Endpoints in Cancer Cachexia Clinical Trials: Systematic Review 6 of the Cachexia Endpoints Series
Abstract Background: In patients receiving anti‐cancer treatment, cachexia results in poorer oncological outcomes. However, there is limited understanding and no…
IMPlications of IMP2 in RNA Biology and Disease
Abstract Insulin-like growth factor 2 mRNA-binding protein 2 (IMP2) is an RNA-binding protein that positively regulates m6A-modified RNAs involved in…
Multicomponent Interventions for Adults With Cancer Cachexia: A Systematic Review
Abstract Background: Cancer cachexia has substantial impacts on people’s quality of life. There is no current gold standard treatment, but…
Efficacy of cannabinoids for the prophylaxis of chemotherapy-induced nausea and vomiting—a systematic review and meta-analysis
Abstract Background: Cannabinoids have potential efficacy as prophylaxis for chemotherapy-induced nausea and vomiting (CINV), but no recent meta-analysis has reported…
Comprehensive analysis of LRRC42 as a potential biomarker and key cellular processes in cancer development
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-88467-6. Article type: Research Article Keywords: LRRC42, Progression biomarker,…
Cannabidiol attenuates lipid metabolism and induces CB1 receptor-mediated ER stress associated apoptosis in ovarian cancer cells
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-88917-1. Article type: Research Article Keywords: Ovarian cancer, Lipid…
A Green Microwave-Assisted Extraction of Cannabis sativa L. Extract and Its Cytotoxic Activity Against
Abstract Objectives: This study aimed to explore the use of D-limonene and some vegetable oils with different amounts of saturated…
Association of Financial Wellness with Patterns of Medical Cannabis Use and Patient-Reported Outcomes in Adults with Cancer
Abstract Objective: Despite increasing use of medical cannabis to manage cancer-related symptoms, U.S. payers do not reimburse medical cannabis, leaving…
Programmed cell death-related gene IL20RA facilitates tumor progression and remodels tumor microenvironment in thyroid cancer
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-87059-8. Article type: Research Article Keywords: Programmed cell death,…