Cannabinoids and Prostate Cancer: A Systematic Review of Animal Studies
Abstract Prostate cancer is a major cause of death among men worldwide. Recent preclinical evidence implicates cannabinoids as powerful regulators…
Advanced cancer
Cannabis Consumption Used by Cancer Patients during Immunotherapy Correlates with Poor Clinical Outcome
Abstract Simple Summary: Cannabis is widely used by patients with cancer to help with cancer symptoms and treatment side effects.…
Activation of Cannabinoid Receptor 2 Prevents Colitis-Associated Colon Cancer through Myeloid Cell De-activation Upstream of IL-22 Production
Abstract Intestinal disequilibrium leads to inflammatory bowel disease (IBD), and chronic inflammation predisposes to oncogenesis. Antigen-presenting dendritic cells (DCs) and…
Identification of MicroRNA-Related Tumorigenesis Variants and Genes in the Cancer Genome Atlas (TCGA) Data
Abstract MicroRNAs (miRNAs) are a class of small non-coding RNA that can down-regulate their targets by selectively binding to the…
TCGA Pan-Cancer Genomic Analysis of Alternative Lengthening of Telomeres (ALT) Related Genes
Abstract Telomere maintenance mechanisms (TMM) are used by cancer cells to avoid apoptosis, 85–90% reactivate telomerase, while 10–15% use the…
Anti-Cancer Potential of Cannabinoids, Terpenes, and Flavonoids Present in Cannabis
Abstract In recent years, and even more since its legalization in several jurisdictions, cannabis and the endocannabinoid system have received…
Oral medicinal cannabinoids to relieve symptom burden in the palliative care of patients with advanced cancer: a double-blind, placebo-controlled, randomised clinical trial of efficacy and safety of 1:1 delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD)
Abstract Background: Despite improvements in medical care, patients with advanced cancer still experience substantial symptom distress. There is increasing interest…
PODXL might be a new prognostic biomarker in various cancers: a meta-analysis and sequential verification with TCGA datasets
Abstract Background: Several studies have investigated the associations between the podocalyxin-like protein (PODXL) expression quantity or locations and cancers survival,…
Genome-Wide Identification and Analysis of Enhancer-Regulated microRNAs Across 31 Human Cancers
Abstract Enhancers are cis-regulatory DNA elements that positively regulate the transcription of target genes in a tissue-specific manner, and dysregulation…
Cannabis, the Endocannabinoid System and Immunity—the Journey from the Bedside to the Bench and Back
Abstract The Cannabis plant contains numerous components, including cannabinoids and other active molecules. The phyto-cannabinoid activity is mediated by the…