Variation in the co-expression profile highlights a loss of miRNA-mRNA regulation in multiple cancer types
Abstract Recent research provides insight into the ability of miRNA to regulate various pathways in several cancer types. Despite their…
Advanced cancer
Cannabinoids as anticancer drugs: current status of preclinical research
Abstract Drugs that target the endocannabinoid system are of interest as pharmacological options to combat cancer and to improve the…
Computing microRNA-gene interaction networks in pan-cancer using miRDriver
Abstract DNA copy number aberrated regions in cancer are known to harbor cancer driver genes and the short non-coding RNA…
DFNA5 regulates immune cells infiltration and exhaustion
Abstract Background: DFNA5 (GSDME) belongs to Gasdermin familily that is involved in a variety of cancers and triggers cell pyroptosis…
Development of a dynamic network biomarkers method and its application for detecting the tipping point of prior disease development
Abstract The dynamic network biomarker (DNB) method has advanced since it was first proposed. This review discusses advances in the…
RFC2: a prognosis biomarker correlated with the immune signature in diffuse lower-grade gliomas
Abstract Diffuse lower-grade gliomas (LGG) represent the highly heterogeneous and infiltrative neoplasms in the central nervous system (CNS). Replication factor…
Cannabidiol (CBD) in Cancer Management
Abstract Simple Summary: Cannabidiol (CBD) is one of the main constituents of the plant Cannabis sativa. Surveys suggest that medicinal…
Cancer Prevalence in E-Cigarette Users: A Retrospective Cross-Sectional NHANES Study
Abstract Background: It is well known that traditional smoking causes various types of cancer, leading to the current decline in…
Cannabinoid and substance relationships of European congenital anomaly patterns: a space-time panel regression and causal inferential study
Abstract With reports from Australia, Canada, USA, Hawaii and Colorado documenting a link between cannabis and congenital anomalies (CAs), this…
Deciphering the etiology and role in oncogenic transformation of the CpG island methylator phenotype: a pan-cancer analysis
Abstract Numerous cancer types have shown to present hypermethylation of CpG islands, also known as a CpG island methylator phenotype…