The Interplay between the Immune and the Endocannabinoid Systems in Cancer
Abstract The therapeutic potential of Cannabis sativa has been recognized since ancient times. Phytocannabinoids, endocannabinoids and synthetic cannabinoids activate two…
Advanced cancer
Functional Fine-Tuning of Metabolic Pathways by the Endocannabinoid System—Implications for Health and Disease
Abstract The endocannabinoid system (ECS) employs a huge network of molecules (receptors, ligands, and enzymatic machinery molecules) whose interactions with…
Molecular Mechanism of Cannabinoids in Cancer Progression
Abstract Cannabinoids are a family of heterogeneous compounds that mostly interact with receptors eliciting several physiological effects both in the…
Different Cannabis sativa Extraction Methods Result in Different Biological Activities against a Colon Cancer Cell Line and Healthy Colon Cells
Abstract Cannabis sativa is one of the oldest medicinal plants used by humans, containing hundreds of bioactive compounds. The biological…
The Complex Interplay between Endocannabinoid System and the Estrogen System in Central Nervous System and Periphery
Abstract The endocannabinoid system (ECS) is a lipid cell signaling system involved in the physiology and homeostasis of the brain…
Cannabis-Derived Compounds Cannabichromene and Δ9-Tetrahydrocannabinol Interact and Exhibit Cytotoxic Activity against Urothelial Cell Carcinoma Correlated with Inhibition of Cell Migration and Cytoskeleton Organization
Abstract Cannabis sativa contains more than 500 constituents, yet the anticancer properties of the vast majority of cannabis compounds remains…
The impact of legalization of access to recreational Cannabis on Canadian medical users with Cancer
Abstract Background: Canada legalized cannabis use for medical purposes in 1999. Legalization of cannabis for recreational purposes in October 2018…
An In Vitro Evaluation of the Molecular Mechanisms of Action of Medical Plants from the Lamiaceae Family as Effective Sources of Active Compounds against Human Cancer Cell Lines
Abstract Simple Summary: Plants have been used in folk medicine for thousands of years. The Lamiaceae family is one of…
Cannabinoids and Prostate Cancer: A Systematic Review of Animal Studies
Abstract Prostate cancer is a major cause of death among men worldwide. Recent preclinical evidence implicates cannabinoids as powerful regulators…
Cannabis Consumption Used by Cancer Patients during Immunotherapy Correlates with Poor Clinical Outcome
Abstract Simple Summary: Cannabis is widely used by patients with cancer to help with cancer symptoms and treatment side effects.…