MicroRNA-targeted reprogramming of CD8+ T cells against cancer
Abstract This scoping review highlights the critical role of microRNAs (miRNAs) in mediating the bidirectional crosstalk between CD8+ T cells…
Advanced cancer
Organelle contact sites in cancer cells
Abstract Membrane contact sites (MCSs) are defined as regions of functional proximity between membranes belonging to the same or different…
The Therapeutic Crossroad Between Mitochondria and Cannabidiol: A Mini-Review
Abstract Cannabidiol is a compound from the plant Cannabis sativa that does not produce psychoactive effects and has increasingly been…
Natural Compounds Derived from Chilean Species and Their Cytotoxic Potential Against Cancer
Abstract Medicinal plants have been used in therapy since ancient times and remain important in human health. Traditionally, they have…
Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in malignant cells
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-026-37119-4. Article type: Research Article Keywords: Biochemistry, Cancer, Cell…
Using a discrete choice experiment to estimate individual preferences to medicate cancer-related symptoms with cannabis
Abstract Background: In October 2018, Canada legalized non-medical cannabis, increasing accessibility nationwide. Although a separate medical cannabis framework exists, many…
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Abstract PIK3R1, a regulatory subunit of class IA phosphoinositide‐3‐kinase (PI3K), undergoes alternative splicing to generate multiple isoforms, primarily p85α and…
Therapeutic potential of acidic cannabinoids: an update
Abstract Cannabis sativa yields a wide range of bioactive compounds, including terpenes, flavonoids, and cannabinoids. Tetrahydrocannabinolic acid (THCA), cannabidiolic acid…
Survey of MaineHealth Cancer Care Network Providers on Cannabis Use: Preparation for Studies Sponsored by the National Cancer Institute
Abstract Introduction: Cannabis and cannabinoid use in patients with cancer has rapidly scaled up over the past decade and is…
Cytotoxicity of Cannabinoids in Combination with Traditional Lymphoma Chemotherapeutic Drugs Against Non-Hodgkin’s Lymphoma
Abstract Background: Cannabinoids (CBs) are FDA-approved for mitigating chemotherapy-induced side effects such as pain, nausea, and loss of appetite. Beyond…