Pericarditis at the crossroads: Unlocking the next wave of therapies
Abstract Pericarditis is an inflammation of the pericardial sac with different aetiologies. While often self-limited, up to 30 % of…
Adjunctive therapy
ZBED4: A Prognostic Biomarker and Therapeutic Target in Hepatocellular Carcinoma
Abstract Background: Hepatocellular carcinoma (HCC) is a prevalent lethal cancer that remains challenging to treat. Therefore, investigation of novel targets…
A Bibliometric Analysis on Research Trends in Paediatric Epilepsy Treatment From 2005 to 2025
Abstract The objective of this bibliometric analysis was to evaluate trends in paediatric epilepsy treatment research from 2005 to 2025.…
The joint role of the immune microenvironment and N7-methylguanosine for prognosis prediction and targeted therapy in acute myeloid leukemia
Abstract Background: The tumor immune microenvironment (TIME) and N7-methylguanosine (m7G) modification play crucial roles in the progression of acute myeloid…
Pan-cancer analysis identifies CLEC12A as a potential biomarker and therapeutic target for lung adenocarcinoma
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s12935-025-03755-5. Article type: Research Article Keywords: CLEC12A, Pan-cancer, Biomarker,…
Predicting therapy dropout in chronic pain management: a machine learning approach to cannabis treatment
Abstract Introduction: Chronic pain affects approximately 30% of the global population, posing a significant public health challenge. Despite their widespread…
Treatment escalation for people with anorexia nervosa: setting, therapies and nutritional interventions
Abstract Purpose of review: Adult patients with severe anorexia nervosa often receive the same unsuccessful treatment without changes regarding the…
Neuropathic pain in cats: Mechanisms and multimodal management
Abstract Clinical approach: Neuropathic pain is suspected if there is abnormal sensation in the area of the distribution of pain,…
Unlocking Overexpressed Membrane Proteins to Guide Breast Cancer Precision Medicine
Abstract Simple Summary: Breast cancer (BC) is a global health concern, hindered by the limited effectiveness and adverse effects of…
Effect of nabiximols oromucosal spray (Sativex®) on symptoms associated with multiple sclerosis-related spasticity: a case series
Abstract Spasticity and its related symptoms of spasms, pain, sleep disturbance and bladder dysfunction are common in persons with multiple…