acute myeloid leukemia (AML)

January 2, 2026

Reawakening Differentiation Therapy in Acute Myeloid Leukemia: A Comprehensive Review of ATRA-Based Combination Strategies

Abstract All-trans retinoic acid (ATRA) is an established differentiation therapy for acute promyelocytic leukemia (APL), but its effect in other…

January 20, 2025

FLT3 is associated with dendritic cell infiltration, tertiary lymphoid structure construction, and predict response to checkpoint inhibitors immunotherapy in solid cancers

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-86185-7. Article type: Research Article Keywords: FLT3, AML, Hepatocellular…

July 28, 2024

Pan-cancer investigation of RFX family and associated genes identifies RFX8 as a therapeutic target in leukemia

Abstract Background: Several transcription factors and co-factors are encoded by the RFX (Regulatory Factor X) family (RFX1-8) and associated genes…

October 1, 2022

LPCAT3 is a potential prognostic biomarker and may be correlated with immune infiltration and ferroptosis in acute myeloid leukemia: a pan-cancer analysis

Abstract Background: Recent studies have highlighted the critical role of lysophosphatidylcholine acyltransferase 3 (LPCAT3) during cancer development. However, the abnormal…