Mechanism of action of the bile acid receptor TGR5 in obesity
Abstract G protein-coupled receptors (GPCRs) are a large family of membrane protein receptors, and Takeda G protein-coupled receptor 5 (TGR5)…
acute inflammation
The Modulated Role of Toxoplasma gondii on Eosinophils in Psychiatric Disorders after Cannabis Cessation
Abstract The aim of our study was to evaluate the impact of T. gondii status on eosinophils count (EOS), the…
A pan-cancer analysis implicates human NKIRAS1 as a tumor-suppressor gene
Abstract κB-Ras proteins inhibit two signaling pathways known to be important for carcinogenesis: NF-κB, a key regulator of inflammation, and…
Topical Cannabidiol and the Progression Rate of Delayed Onset Muscle Soreness
Abstract This study investigated the efficacy of topical cannabidiol (CBD) ointment in reducing localized inflammation, minimizing performance detriments, and attenuating…
Immunomodulation by cannabidiol in bovine primary ruminal epithelial cells
Abstract Background: Ruminant livestock experience a number of challenges, including high concentrate diets, weaning and transport, which can increase their…
Exploring potential anti-inflammatory effects of medicinal cannabis
Abstract Purpose: Inflammation is thought to play a key role in malignant disease and may play a significant part in…
Cannabinoids in the treatment of cancer anorexia and cachexia: Where have we been, where are we going?
Abstract Cachexia–anorexia cancer syndrome remains an unmet clinical need with a dearth of treatment and no standard of care. Acting…
The Anti-Inflammatory Effects of Cannabis sativa Extracts on LPS-Induced Cytokines Release in Human Macrophages
Abstract Inflammation is the response of the innate immune system to any type of injury. Although acute inflammation is critical…
Cannabidiol-Loaded Nanoparticles Based on Crosslinked Starch: Anti-Inflammatory Activity and Improved Nose-to-Brain Delivery
Abstract Cannabidiol (CBD) has previously been shown to inhibit inflammatory cytokine production in both in vitro and in vivo studies…
Antibacterial Activity of a Bioactive Tooth-Coating Material Containing Surface Pre-Reacted Glass in a Complex Multispecies Subgingival Biofilm
Abstract Bioactive materials were developed with the ability to release fluoride and provide some antimicrobial potential, to be widely used…