Introducing the evidence-based population health tool of the Lower-Risk Cannabis Use Guidelines to Brazil
Abstract Cannabis is the most commonly used illegal drug, and is associated with well-documented adverse health outcomes, both acute and…
• access to healthcare and health outcomes of vulnerable populations
The neuropsychopharmacology of cannabis: A review of human imaging studies
Abstract The laws governing cannabis are evolving worldwide and associated with changing patterns of use. The main psychoactive drug in…
Chemical fingerprinting of single glandular trichomes of Cannabis sativa by Coherent anti-Stokes Raman scattering (CARS) microscopy
Abstract Background: Cannabis possesses a rich spectrum of phytochemicals i.e. cannabinoids, terpenes and phenolic compounds of industrial and medicinal interests.…
Anti-Inflammatory Activity in Colon Models Is Derived from Δ9-Tetrahydrocannabinolic Acid That Interacts with Additional Compounds in Cannabis Extracts
Abstract Introduction: Inflammatory bowel diseases (IBDs) include Crohn’s disease, and ulcerative colitis. Cannabis sativa preparations have beneficial effects for IBD…
Affinity and Efficacy Studies of Tetrahydrocannabinolic Acid A at Cannabinoid Receptor Types One and Two
Abstract Introduction:Cannabis biosynthesizes Δ9-tetrahydrocannabinolic acid (THCA-A), which decarboxylates into Δ9-tetrahydrocannabinol (THC). There is growing interest in the therapeutic use of…
Targeting calcium signaling in cancer therapy
Abstract The intracellular calcium ions (Ca2+) act as second messenger to regulate gene transcription, cell proliferation, migration and death. Accumulating…
Project ECHO (Extension for Community Healthcare Outcomes): A new model for educating primary care providers about treatment of substance use disorders
Abstract Background: Project ECHO (Extension for Community Healthcare Outcomes) trains and mentors primary care providers (PCPs) in the care of…
Pathways from Cannabis to Psychosis: A Review of the Evidence
Abstract The nature of the relationship between cannabis use (CU) and psychosis is complex and remains unclear. Researchers and clinicians…