The neuropsychopharmacology of cannabis: A review of human imaging studies
Abstract The laws governing cannabis are evolving worldwide and associated with changing patterns of use. The main psychoactive drug in…
• access to healthcare and health outcomes of vulnerable populations
Big-data analysis: A clinical pathway on endoscopic retrograde cholangiopancreatography for common bile duct stones
Abstract BACKGROUND: A clinical pathway (CP) is a standardized approach for disease management. However, big data-based evidence is rarely involved…
Outcomes of endoscopic sphincterotomy vs open choledochotomy for common bile duct stones
Abstract BACKGROUND: Endoscopic sphincterotomy (EST) for the management of common bile duct stones (CBDS) is used increasingly widely because it…
Chemical fingerprinting of single glandular trichomes of Cannabis sativa by Coherent anti-Stokes Raman scattering (CARS) microscopy
Abstract Background: Cannabis possesses a rich spectrum of phytochemicals i.e. cannabinoids, terpenes and phenolic compounds of industrial and medicinal interests.…
Anti-Inflammatory Activity in Colon Models Is Derived from Δ9-Tetrahydrocannabinolic Acid That Interacts with Additional Compounds in Cannabis Extracts
Abstract Introduction: Inflammatory bowel diseases (IBDs) include Crohn’s disease, and ulcerative colitis. Cannabis sativa preparations have beneficial effects for IBD…
Affinity and Efficacy Studies of Tetrahydrocannabinolic Acid A at Cannabinoid Receptor Types One and Two
Abstract Introduction:Cannabis biosynthesizes Δ9-tetrahydrocannabinolic acid (THCA-A), which decarboxylates into Δ9-tetrahydrocannabinol (THC). There is growing interest in the therapeutic use of…
Targeting calcium signaling in cancer therapy
Abstract The intracellular calcium ions (Ca2+) act as second messenger to regulate gene transcription, cell proliferation, migration and death. Accumulating…
Project ECHO (Extension for Community Healthcare Outcomes): A new model for educating primary care providers about treatment of substance use disorders
Abstract Background: Project ECHO (Extension for Community Healthcare Outcomes) trains and mentors primary care providers (PCPs) in the care of…
Effects of waterborne nickel on the physiological and immunological parameters of the Pacific abalone Haliotis discus hannai during thermal stress
Abstract In this study, the 96-h LC50 at 22 and 26 °C values was 28.591 and 11.761 mg/L, respectively, for…
Pathways from Cannabis to Psychosis: A Review of the Evidence
Abstract The nature of the relationship between cannabis use (CU) and psychosis is complex and remains unclear. Researchers and clinicians…