Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies
Abstract Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and bioavailability of poorly water-soluble drugs. Various approaches have…
Abiotic stress
Calcium Signaling in Plant Programmed Cell Death
Abstract Programmed cell death (PCD) is a process intended for the maintenance of cellular homeostasis by eliminating old, damaged, or…
Reasons for cannabidiol use: a cross-sectional study of CBD users, focusing on self-perceived stress, anxiety, and sleep problems
Abstract Background: Public and medical interest in cannabidiol (CBD) has been rising, and CBD is now available from various sources.…
The effectiveness of inhaled Cannabis flower for the treatment of agitation/irritability, anxiety, and common stress
Abstract Background: An observational research design was used to evaluate which types of commonly labeled Cannabis flower product characteristics are…
Cannabis vapor self-administration elicits sex- and dose-specific alterations in stress reactivity in rats
Abstract Rationale: Cannabis users frequently report stress relief as their primary reason for use. Recent studies indicate that human cannabis…
Ibudilast for alcohol use disorder: study protocol for a phase II randomized clinical trial
Abstract Background: Alcohol use disorder (AUD) is a chronic and relapsing condition for which current pharmacological treatments are only modestly…
The Effectiveness of Cannabis Flower for Immediate Relief from Symptoms of Depression
Abstract Objective: Scientific research on how consumption of whole, natural Cannabis flower affects low mood and behavioral motivations more generally…
Drug-induced stress responses and addiction risk and relapse
Abstract A number of studies have assessed the effects of psychoactive drugs on stress biology, the neuroadaptations resulting from chronic…
Interaction Between Stress and Addiction: Contributions From Latin-American Neuroscience
Abstract Drug addiction is a chronic neuropsychiatric disorder that escalates from an initial exposure to drugs of abuse, such as…
Diminished positive affect and traumatic stress: A biobehavioral review and commentary on trauma affective neuroscience
Abstract Post-traumatic stress manifests in disturbed affect and emotion, including exaggerated severity and frequency of negative valence emotions, e.g., fear,…