Role of Cannabidiol for Improvement of the Quality of Life in Cancer Patients: Potential and Challenges
Abstract There is currently a growing interest in the use of cannabidiol (CBD) to alleviate the symptoms caused by cancer,…
abdominal pain
The association between cannabis and codeine use: a nationally representative cross-sectional study in Canada
Abstract Background: Due to the growing use of cannabis for the purposes of pain relief, evidence is needed on the…
Herbal Approaches to Pediatric Functional Abdominal Pain
Abstract Chronic abdominal pain is one of the most common problems seen by both pediatricians and pediatric gastroenterologists. Abdominal-pain-related functional…
Cannabidivarin alleviates neuroinflammation by targeting TLR4 co-receptor MD2 and improves morphine-mediated analgesia
Abstract Toll-like receptor 4 (TLR4) is a pattern-recognition receptor (PRR) that regulates the activation of immune cells, which is a…
Perspectives on Challenges in Cannabis Drug Delivery Systems: Where Are We?
Abstract Cannabis and its natural derivatives have emerged as promising therapeutics for multiple pathological and nonpathological medical conditions. For example,…
Druggable Targets and Compounds with Both Antinociceptive and Antipruritic Effects
Abstract Pain and itch are both important manifestations of various disorders, such as herpes zoster, atopic dermatitis, and psoriasis. Growing…
Anti-Inflammatory and Analgesic Properties of the Cannabis Terpene Myrcene in Rat Adjuvant Monoarthritis
Abstract Cannabis-based terpenes are believed to modulate physiological responses to disease and alter the efficacy of cannabinoids in the so-called…
Tetrahydrocannabinol and cannabidiol medicines for chronic pain and mental health conditions
Abstract Combination tetrahydrocannabinol (THC)/cannabidiol (CBD) medicines or CBD-only medicines are prospective treatments for chronic pain, stress, anxiety, depression, and insomnia.…
Cannabinoid Effect and Safety in Spasticity Following Stroke: A Double-Blind Randomized Placebo-Controlled Study
Abstract Background: Nabiximols is a cannabis-based drug to treat spasticity-associated symptoms currently approved for patients with multiple sclerosis only. Cannabinoids…
Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation
Abstract Background: Cannabinoid hyperemesis syndrome (CHS) is a diagnosis of exclusion with intractable nausea, cyclic vomiting, abdominal pain, and hot…