ABCD Study

August 18, 2025

The impact of physical activity on substance use experimentation and initiation among adolescents: Results from the ABCD Study® cohort

Abstract Physical Activity (PA) is important for mental, physical, and brain health. Adolescence is marked by increased engagement in risky…

August 15, 2024

A disintegrin and metalloproteinase domain 10 expression inhibition by the small molecules adenosine, cordycepin and N6, N6-dimethyladenosine and immune regulation in malignant cancers

Abstract A disintegrin and metalloproteinase domain 10 (ADAM10), a member of the ADAM family, is a cellular surface protein with…

July 4, 2024

Independent and Interactive Impacts of Prenatal Exposure to Legal Substances and Childhood Trauma on Emotion Processing in Pre-Adolescents: Preliminary Findings From the ABCD Study

Abstract Objective: This paper investigated the effects of prenatal drug exposure (PDE), childhood trauma (CT), and their interactions on the…

January 8, 2024

Impact of prenatal marijuana exposure on adolescent brain structural and functional connectivity and behavioural outcomes

Abstract There has been an increase in the number of women using marijuana whilst pregnant. Previous studies have shown that…

November 24, 2022

NUDT7 regulates total hepatic CoA levels and the composition of the intestinal bile acid pool in male mice fed a Western diet

Abstract Nudix hydrolase 7 (NUDT7) is an enzyme that hydrolyzes CoA species, is highly expressed in the liver, and resides…

November 15, 2022

Substance use patterns in 9 to 13-year-olds: Longitudinal findings from the Adolescent Brain Cognitive Development (ABCD) study

Abstract The ABCD Substance Use Workgroup describes substance use patterns within the cohort. The ABCD cohort is entering adolescence and…

April 7, 2022

The dimerization mechanism of the N-terminal domain of spider silk proteins is conserved despite extensive sequence divergence

Abstract The N-terminal (NT) domain of spider silk proteins (spidroins) is crucial for their storage at high concentrations and also…

November 30, 2021

In-situ and Real-Time Monitoring of the Interaction Between Lysins and Staphylococcus aureus Biofilm by Surface Plasmon Resonance

Abstract Staphylococcus aureus can produce a multilayered biofilm embedded in extracellular polymeric matrix. This biofilm is difficult to remove, insensitive…

August 17, 2021

Structural and functional variation of chitin-binding domains of a lytic polysaccharide monooxygenase from Cellvibrio japonicus

Abstract Among the extensive repertoire of carbohydrate-active enzymes, lytic polysaccharide monooxygenases (LPMOs) have a key role in recalcitrant biomass degradation.…