Heads Up: Transcriptomics Reveal Functional Roles of Cannabis Glandular Trichome Stalks
Abstract Cannabis sativa glandular trichomes (CsGT) are the primary sites of cannabinoid biosynthesis. They consist of a metabolically active head…
ABC transporters
Trends in Antidepressant, Anxiolytic, and Cannabinoid Use Among Italian Elite Athletes (2011–2023): A Longitudinal Anti-Doping Analysis
Abstract Mental health disorders, particularly depression and anxiety, have become increasingly prevalent among elite athletes, exacerbated by factors such as…
Are Δ9-Tetrahydrocannabinol and Its Major Metabolites Substrates or Inhibitors of Placental or Human Hepatic Drug Solute-Carrier Transporters?
Abstract Δ9-Tetrahydrocannabinol (THC) is the primary psychoactive component of cannabis which is being increasingly consumed by pregnant people. In humans,…
Cannabinoid-Inspired Inhibitors of the SARS-CoV-2 Coronavirus 2′-O-Methyltransferase (2′-O-MTase) Non-Structural Protein (Nsp10–16)
Abstract The design and synthesis of antiviral compounds were guided by computationally predicted data against highly conserved non-structural proteins (Nsps)…
Effect of Stanozolol and/or Cannabis Abuse on Hypertrophic Mechanism and Oxidative Stress of Male Albino Rat Cardiac Tissue in Relation to Exercise: A Sport Abuse Practice
Abstract Adolescents commonly co-abuse many drugs including anabolic androgenic steroids either they are athletes or non-athletes. Stanozolol is the major…
Characterization and expression analysis of MATEs in Cannabis sativa L. reveals genes involving in cannabinoid synthesis
Abstract The medicinal plant Cannabis sativa L. (C. sativa) accumulates plant cytotoxic but medicinally important cannabinoids in glandular trichomes and…
Sorafenib Chemosensitization by Caryophyllane Sesquiterpenes in Liver, Biliary, and Pancreatic Cancer Cells: The Role of STAT3/ABC Transporter Axis
Abstract A combination of anticancer drugs and chemosensitizing agents has been approached as a promising strategy to potentiate chemotherapy and…
Effects of Cannabidiol on Exercise Physiology and Bioenergetics: A Randomised Controlled Pilot Trial
Abstract Background: Cannabidiol (CBD) has demonstrated anti-inflammatory, analgesic, anxiolytic and neuroprotective effects that have the potential to benefit athletes. This…
Peroxisomal ABC Transporters: An Update
Abstract ATP-binding cassette (ABC) transporters constitute one of the largest superfamilies of conserved proteins from bacteria to mammals. In humans,…
(Endo)Cannabinoids and Gynaecological Cancers
Abstract Simple Summary: Cancers of the female reproductive system are common and are responsible for a large number of deaths…