Antiproliferative Effect of Okra Seed Protein Isolate against HepG2 and A549 Cell Lines
Abstract Cancer is a non‐communicable disease and is one of the leading causes of mortality worldwide. While plant‐derived compounds have…
a prospective alternate to cannabinoids
Delta-9-Tetrahydrocannabinol Blocks Bone Marrow-Derived Macrophage Differentiation through Elimination of Reactive Oxygen Species
Abstract Macrophages are vital components of the immune system and serve as the first line of defense against pathogens. Macrophage…
Adjustments of the Phytochemical Profile of Broccoli to Low and High Growing Temperatures: Implications for the Bioactivity of Its Extracts
Abstract Climate change causes shifts in temperature patterns, and plants adapt their chemical content in order to survive. We compared…
The Effectiveness and Safety of Medical Cannabis for Treating Cancer Related Symptoms in Oncology Patients
Abstract The use of medical cannabis (MC) to treat cancer-related symptoms is rising. However, there is a lack of long-term…
Cannabis sativa Extract Induces Apoptosis in Human Pancreatic 3D Cancer Models: Importance of Major Antioxidant Molecules Present Therein
Abstract In recent years, interest in Cannabis sativa L. has been rising, as legislation is moving in the right direction.…
Adherence, Safety, and Effectiveness of Medical Cannabis and Epidemiological Characteristics of the Patient Population: A Prospective Study
Abstract Background: Despite the absence of rigorous prospective studies, there has been an increase in the use of cannabis-based medicinal…
Reconstruction and Analysis of the Immune-Related LINC00987/A2M Axis in Lung Adenocarcinoma
Abstract Enhancer RNAs (eRNAs) participate in tumor growth and immune regulation through complex signaling pathways. However, the immune-related function of…
Patient-Derived Mutant Forms of NFE2L2/NRF2 Drive Aggressive Murine Hepatoblastomas
Abstract Background & Aims: Hepatoblastoma (HB), the most common pediatric liver cancer, often bears β-catenin mutations and deregulates the Hippo…
Cannabidiol Protects Dopaminergic Neuronal Cells from Cadmium
Abstract The protective effect of cannabidiol (CBD), the non-psychoactive component of Cannabis sativa, against neuronal toxicity induced by cadmium chloride…
Perilipin 5 Protects against Cellular Oxidative Stress by Enhancing Mitochondrial Function in HepG2 Cells
Abstract Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases worldwide. Reactive oxygen species (ROS), as…