Abstract Corticobasal degeneration typically progresses gradually over 5–7 years from onset till death. Fulminant corticobasal degeneration cases with a rapidly…
Abstract Introduction: Chronic traumatic encephalopathy (CTE) is a tauopathy associated to repetitive head trauma. There are no validated in vivo…
Abstract Electronic supplementary material: The online version of this article (10.1186/s40478-019-0691-9) contains supplementary material, which is available to authorized users.…
Abstract Pathological tau aggregates in Alzheimer’s disease (AD) and frontotemporal lobar degeneration-tau (FTLD-tau) adopt distinct conformations differentiated by the AD-tau…
Abstract Background: The innate immune system is known to be involved early in the pathogenesis of Alzheimer’s disease (AD) and…
Abstract Mesenchymal stem cells (MSCs) have emerged as a promising tool for the treatment of several neurodegenerative disorders, including Alzheimer’s…
Abstract The CB2 receptor is one of the components of the endogenous cannabinoid system, a complex network of signaling molecules…
Abstract Background: Tauopathies are a group of neurodegenerative disorders with accumulation of three-repeat (3R) or four-repeat (4R) Tau. While 3R…