Pro-apoptotic gene BAX is a pan-cancer predictive biomarker for prognosis and immunotherapy efficacy
Abstract Background: Apoptosis Regulator BCL2 Associated X (BAX) is a pro-apoptotic gene. Apoptosis is one of the important components of…
2D demodulation data treatment
The Perspective of Cannabidiol in Psoriasis Therapy
Abstract Psoriasis is a chronic skin condition that can significantly impact the quality of life of those affected. As an…
Effectiveness of cannabis use and cannabis use disorder interventions: a European and international data synthesis
Abstract This data synthesis examined the effectiveness of behavioural and pharmacological approaches for cannabis treatment. We integrated findings from high…
SLAMF8 can predict prognosis of pan-cancer and the immunotherapy response effectivity of gastric cancer
Abstract SLAMF8, the eighth member of the Signaling Lymphocytic Activation Molecule Family (SLAMF), functions in the regulation of the development…
Single-cell analysis defines highly specific leukemia-induced neutrophils and links MMP8 expression to recruitment of tumor associated neutrophils during FGFR1 driven leukemogenesis
Abstract Background: Leukemias driven by activated, chimeric FGFR1 kinases typically progress to AML which have poor prognosis. Mouse models of…
An observational time-series study on the behavioral effects of adjunctive artisanal cannabidiol use by adults with treatment resistant epilepsies
Abstract Background: For approximately 30% of people with epilepsy, seizures are not well-controlled by anti-seizure medication (ASM). This condition, called…
Pharmacodynamic rationale for the choice of antiseizure medications in the paediatric population
Abstract In the landscape of paediatric epilepsy treatment, over 20 anti-seizure medications (ASMs) have gained approval from Drug Regulatory Agencies,…
Oral Cannabidiol for Seborrheic Dermatitis in Patients With Parkinson Disease: Randomized Clinical Trial
Abstract Background: Seborrheic dermatitis (SD) affects 18.6%-59% of persons with Parkinson disease (PD), and recent studies provide evidence that oral…
A qualitative study of the implementation and organization of the national Greenlandic addiction treatment service
Abstract Background: Alcohol and cannabis use constitutes the major public health problems in Greenland. Thus, it is important to assess…
Where we live matters: a comparison of chronic pain treatment between remote and non-remote regions of Quebec, Canada
Abstract Objective: Where a person lives is a recognized socioeconomic determinant of health and influences healthcare access. This study aimed…