Abstract Cannabis legalization continues to progress in the USA for medical and recreational purposes. G protein-coupled receptor 55 (GPR55) is…
Abstract Background: Cuprotosis is a newly discovered form of cell death that differs from other types of cell death. The…
Abstract Background: Substance use/abuse is a global challenge that has detrimental effects on nations’ health, wealth, and security. Substance users…
Abstract The endocannabinoid system is widely expressed throughout the body and is comprised of receptors, ligands, and enzymes that maintain…
Abstract Background: Cannabis addiction is a chronically relapsing disorder lacking effective treatment. Regular cannabis consumption typically begins during adolescence, and…
Abstract The cation-permeable TRPV2 channel is important for cardiac and immune cell function. Cannabidiol (CBD), a non-psychoactive cannabinoid of clinical…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00213-023-06360-4. Article type: Review Article Keywords: Cannabis, Cannabis smoking,…
Abstract Background Chronic steroid use is debilitating to health, but, in some cases, it is necessary. We examined the effect…
Abstract We have established for the first time a mouse model of cannabinoid addiction using WIN 55,212–2 intravenous self-administration (0.0125…
Abstract Introduction: Chronic or uncontrolled activation of myeloid cells including monocytes, macrophages and dendritic cells (DCs) is a hallmark of…