Abstract We investigated the influence of cannabidiol (CBD) on blood pressure (BP) and heart rate (HR) in spontaneously (SHR) and…
Abstract Various studies performed in cultured cells and in in vivo models of neuronal damage showed that cannabinoids exert a…
Abstract Background: The endocannabinoid system (ECS) is a major regulator of synaptic plasticity and neuromodulation. Alterations of the ECS have…
Abstract The plant Cannabis sativa contains cannabinoids represented by Δ9-tetrahydrocannabinol, which exert psychoactivity and immunomodulation through cannabinoid CB1 and CB2…
Abstract Elucidating the underlying molecular mechanisms regulating fear and extinction learning may offer insights that can lead to novel treatments…
Abstract Endocannabinoids have been identified to have roles in numerous physiological and pathological processes. Largely due to the association of…
Abstract Depression and pain co-exist in almost 80% of patients and are associated with impaired health-related quality of life, often…
Abstract Chemotherapy-induced nausea is one of the most distressing symptoms reported by patients undergoing treatment, and even with the introduction…
Abstract Endocannabinoids including anandamide and 2-arachidonoylglycerol are involved in cancer pathophysiology in several ways, including tumor growth and progression, peritumoral…
Abstract Atherosclerosis is responsible for most cardiovascular disease (CVD) and is caused by several factors including hypertension, hypercholesterolemia, and chronic…